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Nervous System Disorders > On-off Effect, On-off Phenomena

The following information is about On-off Effect, On-off Phenomena.

On-off Effect, On-off Phenomena Defined

A change in the patient's condition, with sometimes rapid fluctuations between uncontrolled movements and normal movement, usually occurring after long-term use of levodopa and probably caused by changes in the ability to respond to this drug.

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